Word: estrogenous
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Dates: during 2000-2009
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More bad news for hormone-replacement therapy. The FDA has asked makers of HRT pills (most of which contain the hormones progestin and estrogen) to add another warning to their labels: that HRT may raise the risk of dementia in older women. A watershed 2002 study had already linked the drugs to increased risk of breast cancer, heart attack and stroke, leading experts to conclude that for many women the risks of long-term use outweigh the benefits. The recent FDA directive was based on data published last year in the Journal of the American Medical Association showing that women...
...impotence. Both sexes experience failures as they age. And any number of health factors may be at fault, including poor circulation, diabetes, high blood pressure, heart disease, stress and alcoholism--to say nothing of the medications often prescribed for them. For women, the problem is often a decline in estrogen at menopause, usually around age 50. That may cause disconcerting hot flashes as well as dryness and a thinning of the vaginal wall that can make intercourse unpleasurable, if not painful. Production of the male sex hormone testosterone--which occurs in both sexes--also drops, and with that may come...
...lawyers talk these days about Viagra affairs and split-ups. Some doctors are prescribing testosterone as a libido booster for so-called low-T women, helping push up testosterone sales some 17 times in the past decade to about $400 million annually. Variously given as a pill combined with estrogen or as a patch, cream or injection, testosterone remains unproven as a sex aid. Meanwhile, it can cause oily skin, unwanted facial hair, a lowered voice and an upsetting onslaught of sexual fantasies...
BREAST: A group of drugs called aromatase inhibitors that were once used to treat metastatic breast cancer is helpful in less advanced cases as well. They target tumors that need estrogen by lowering the amount of estrogen in the body. Women who took aromatase inhibitors for five years after taking tamoxifen (which also shrinks estrogen-sensitive tumors) reduced their risk of recurrence by almost half...
Last year put a few more nails in the coffin of long-term hormone-replacement therapy. Further examination of the data from the Women's Health Initiative, a study that involved more than 16,000 women, showed that the combination of estrogen and progestin not only raised a postmenopausal woman's risk of heart disease and breast cancer but also increased her risk of stroke and doubled her chances of developing dementia if she was 65 or older. The grim research results, on top of those released in 2002, have translated into plummeting prescriptions for Wyeth Pharmaceuticals, manufacturer of Prempro...