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Research published in Thursday's issue of the journal Nature suggests that the cloned ewe named Dolly could be -- as an observer once joked -- a sheep in lamb's clothing. The three-year-old Finn Dorset ewe, it turns out, may be susceptible to premature aging. Researchers have determined that chromosome tips, known as telomeres, which regulate the lifespan of cells by preventing their genetic code from fraying, are shorter than expected in Dolly. Researchers are not sure whether the "older DNA" is the result of the age of the animal from which Dolly was cloned or the result...

Author: /time Magazine | Title: Oh, No! Dolly the Sheep is Getting Wrinkly! | 5/26/1999 | See Source »

...Scottish researchers clone a sheep named Dolly from cells of an adult ewe...

Author: /time Magazine | Title: A Century of Science | 3/29/1999 | See Source »

...Wilmut did it. From a single mammary cell, taken from an adult ewe, he and his colleagues at the Roslin Institute cloned a sheep called Dolly and introduced her to a skeptical world in February...

Author: /time Magazine | Title: Ian Wilmut: Breaking The Clone Barrier | 3/29/1999 | See Source »

Nearly two years after the cloning of Dolly had everyone asking if there would ever be another ewe, South Korean researchers are claiming that the answer is yes. Using a technique already performed in Hawaii on mice, two Korean scientists have conducted what may be the first cloning of a human embryo. They implanted genetic material from a 30-year-old woman into an egg cell, and then let that cell divide twice before stopping the experiment to steer clear of a Korean ban on experimentation with more fully developed embryos. "What this represents is a refinement of the Hawaii...

Author: /time Magazine | Title: Korean Researchers Claim Human Clone | 12/17/1998 | See Source »

Extraordinary claims, scientists like to say, require extraordinary proof, and none has been more extraordinary in recent years than Scottish embryologist Ian Wilmut's claim that he and his colleagues had cloned a sheep named Dolly from a mammary cell of a pregnant ewe. More than a year later, nobody has managed to reproduce the Dolly experiment, and Wilmut is under growing pressure to prove that his famous sheep is what he says she is. Last week at a genetics meeting at the University of Louisville, in Kentucky, he blandly conceded that there was a "remote possibility" that there could...

Author: /time Magazine | Title: Was Dolly a Mistake? | 3/2/1998 | See Source »

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