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...initial impetus for the research came from a rather oblique direction. UCSD Biochemist Marlene DeLuca has been investigating for 20 years how the firefly protein -- in this case, an enzyme called luciferase -- produces light. But the process of collecting and grinding up fireflies to extract the enzyme was laborious and costly. She and Donald Helinski, a molecular geneticist, decided to isolate the luciferase gene, cloning exact copies of it and splicing it into the genetic machinery of the common bacterium E. coli. The E. coli could then massproduce luciferase by the vat. DeLuca and Helinski accomplished this task by using...

Author: /time Magazine | Title: Science: Of Fireflies and Tobacco Plants | 11/17/1986 | See Source »

Subsequent experiments showed that the mysterious substance was also present in snake venom and mouse salivary glands. It was left to Cohen, a pipe-smoking individualist, to extract the first pure samples of the protein now known as nerve growth factor. Later, working separately, Cohen discovered epidermal growth factor, which governs cell development in the skin. He also located a protein on the surfaces of cells that acts as a receptor...

Author: /time Magazine | Title: MEDICINE: Lives of Spirit and Dedication | 10/27/1986 | See Source »

...beautiful. Not only would millions of the hungry be fed, but never again would I bite into a sour piece of rubber or peel apart a burger in order to extract the urethane substance like a pair of dirty diapers. Millions and millions of Americans would share in the jubilation. For the few who actually liked the pickles, they would be making a minor sacrifice for a grand cause...

Author: By Bruce M. Kluckhohn, | Title: Soured World View | 7/1/1986 | See Source »

...were many. His relations with the powers that were do not seem to have been easy. In 1477 he renounced his Nuremberg citizenship and departed for Cracow, in Poland, where he worked for nearly 20 years. In 1503, after getting back to Nuremberg, he forged a promissory note to extract money from a businessman he believed had cheated him; Stoss, by now a man in his late 50s or early 60s, was branded on both cheeks for that. In later years he was in and out of dungeon and lived under a cloud of civic disapproval, while Durer, some...

Author: /time Magazine | Title: Art: Out of Gothic, into the Future | 5/26/1986 | See Source »

This year was worse than most: informed of their lottery numbers several days before they were required to submit their housing bids, the freshman class engaged in a frezy of second-guessing in an effort to extract the maximum punch from their given number. Fake housing surveys were conducted by yardlings posing, variously, as members of The Crimson, the Independent, the Housing Office, the Freshman Dean's Office, and, amazingly, the Statistics Department. The whole thing need never have happened...

Author: By Robert M. Neer, | Title: Freshman Stats 101 | 4/24/1986 | See Source »

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