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...lengthy extract in the Harvard Business Review prompted a fusillade from fervent free-traders. New Republic columnist (and TIME contributor) Michael Kinsley broadly hinted that Choate, despite his denials, was engaging in "McCarthyism" with "his easy accusations of disloyalty, his imagery of infection of the body politic, his woozy mixture of falsehoods, half-truths and exaggerations." Hobart Rowen, a Washington Post columnist, called Choate's theories "pure poppycock...
Rosenberg's strategy, devised with the help of Anderson, is to extract immune cells called tumor-infiltrating lymphocytes (TILs) from the tumors of melanoma patients. Rosenberg bathes the TILs in a solution of interleukin-2, a natural substance that invigorates them, and then exposes the TILs to re- engineered mouse leukemia retroviruses...
Half the compounds are manufactured by chemical and pharmaceutical companies; the rest are provided by botanists and ethnobiologists who collect folk medicines and exotic living materials like the bark of the Pacific yew tree, from which scientists extract Taxol, shown to be effective against ovarian cancer cells. The researchers are looking for "natural" cell killers harvested from such remote locations as the Brazilian rain forest and Australia's Great Barrier Reef. Even ground-up seashells, sponges and coral starfish are studied for chemicals that might show some ability to fight cancer...
...Rosenberg technique, used in dozens of U.S. cancer centers, is to extract some of a patient's white blood cells and bathe them in interleukin-2, a hormone that stimulates them, turning them into lymphokine-activated killer, or LAK, cells. Injected back into the bloodstream along with repeated doses of interleukin-2, they attack any foreign cells (including malignant ones) with great vigor. The technique has caused tumors to shrink significantly in a number of advanced melanoma patients and has apparently even effected an occasional cure...
...Administration and Middle East moderates, including Egypt's Hosni Mubarak and Jordan's King Hussein, feel that the best antidote to Saddam's potential barbarity is to keep him engaged in dialogue. In November 1988 the U.S. used quiet diplomacy to extract from Saddam a promise that he would not be first, in future, to use chemical weapons. Despite his confrontational tone in Baghdad last week, Saddam signed on to a watered-down communique that fell short of his call for oil sanctions against the U.S. That was only a minor victory for the region's moderates, who have much...