Word: falciparum
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...high of 160). A total of 213 cases was reported; of those, only six were of the "benign tertian" or vivax type. All other cases were caused by the far more virulent parasite, Plasmodium falciparum, which sets off violent fevers and may make a fatal attack on the brain, spleen or other organs...
...month of October, and the total for November will probably be much higher. Hundreds of victims have already been evacuated to military hospitals around the Pacific because the armed forces routinely evacuate any man who is not expected to be able to return to duty within 30 days, and falciparum-malaria treatment and convalescence take from five to eight weeks...
Back to Quinine. Medically, the most disturbing aspect of malaria in Viet Nam is the appearance of falciparum parasites that are resistant to chloroquine, which was hailed only a few years ago as the almost perfect antimalarial drug. U.S. servicemen take a weekly prophylactic tablet containing 300 mg. of chloroquine and 45 mg. of another antimalarial known as primaquine. If they develop malaria despite this, they are likely to be infected by a resistant strain of parasites. If massive doses of chloroquine fail to bring the fever down within a few hours, the medics may switch to pyrimethamine (Daraprim), which...
...that shows some promise is DOS (diaphenylsulfone), normally used in leprosy. Another is a new, long-acting sulfa drug, Fanasil. Malariologists are running tests with prison volunteers to see whether DDS or Fanasil can be used, probably in combination with pyrimethamine, to beat back the chloroquine resistance of falciparum parasites in much of Southeast Asia...
...twelve have been killed and 58 are missing. Upland malaria is the more dangerous variety. On the coastal plains, three out of four cases are of the "benign tertian" variety caused by the parasite Plasmodium vivax, and only one case out of four is "malignant tertian," caused by Plasmodium falciparum. In the hills, the proportions are reversed. Falciparum malaria usually does not last as long as the vivax form-only weeks or months, instead of years-but it is far more disabling while it lasts, and if untreated may cause death. No American serviceman goes untreated. Military discipline requires that...