Word: fat
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Dates: during 1980-1989
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...when the inmates took their grotesque pleasures with a trapped staff member, this "bastard son of a hundred maniacs" worked as a school janitor in Springwood, U.S.A., where his hobby was kidnaping and murdering teenagers. Tried for these crimes, he was freed on a technicality: "Oh, the lawyers got fat and the judge got famous, but somebody forgot to sign the search warrant in the right place." So the parents of Elm Street tracked the demon down to his boiler room and burned him -- to death, some...
They also provide individual spotlights. Page is uproarious as he explains to an unseen partner that he cannot love her because Your Feet's Too Big, and he and De Shields are a hoot expressing scorn and envy for a rival whom they see as Fat and Greasy. De Shields belts 'T Ain't Nobody's Biz-Ness If I Do in an up tempo that may be delightfully surprising to fans of Billie Holiday's torchy rendition, and revels in marijuana in The Viper's Drag. Woodard, too little used, nonetheless glows in Keepin' Out of Mischief Now, while...
Debra Winger, Amy Irving, Rosanna Arquette: moviemakers should be begging to ! snare these actresses for fat and sassy leading roles. No such luck. Irving has for a dozen years commuted easily between stage (Amadeus, The Road to Mecca) and screen (Carrie, Yentl), but movies have rarely caught her witchy allure. Arquette seemed a cinch for stardom after Desperately Seeking Susan, but her elfin sensuality has proved too weird for mainstream fare. As for the wondrous Winger, she anchored three big hits of the early '80s. But after Urban Cowboy, An Officer and a Gentleman and Terms of Endearment, her career...
...with dissolvable plastic wafers that are implanted in the brain and slowly release an antitumor drug for cancer victims. The day is not far off when most diabetics will be able to give themselves insulin with a nasal spray. In California doctors are working on drug-loaded bubbles of fat that bind themselves to diseased cells. Says Robert Langer, a biomedical engineer at M.I.T.: "It's an explosive field with enormous potential...
While the polymer and spray systems stress control and timing, others -- such as those being tested at the Cancer Research Institute of the University of California at San Francisco -- attempt to deliver specific drugs to specific cells. To accomplish this, microscopic bubbles of fat, called liposomes, are filled with a cancer drug and attached to antibodies that have the ability to distinguish cancer cells from healthy cells. Injected, the package ignores normal cells and attaches to diseased ones. But getting the liposomes to stay in the blood long enough to do their job has been difficult until now. Researchers seem...