Word: fats
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...shows is that the bones also act as a kind of endocrine organ. They release a hormone called osteocalcin that not only acts locally to influence bone formation, but also increases the production of insulin in the pancreas, raises the body's sensitivity to insulin and reduces stores of fat...
...endocrinologist at the National Institute of Diabetes and Digestive and Kidney Disorders. "The skeleton used to be thought of as just a structural support system. This opens the door to a new way of seeing the bones." The finding parallels discoveries in the 1990s about the metabolic activities of fat - another body tissue that was once seen as inert...
Karsenty became intrigued by the relationship between fat and bone after showing in 2002 how leptin, a hormone secreted by fat cells, influences bone formation. Leptin is best known as a regulator of body weight and appetite. Karsenty reasoned that if fat influences bone, then the reverse must be true. And, he says, there was another clue to the relationship: "We were using the observation that obese people are [relatively] protected from osteoporosis...
...some ways it's logical that bone and fat tissue would talk to each other. "Obviously there does need to be some coordination between skeletal growth and body mass," says C. Ronald Kahn, director of the Joslin Diabetes Center at Harvard. "If you carry around extra weight, your bones need to hold up under the extra pressure, so it's not surprising that your bones have a sense of body fat...
...Good Will Hunting, all of them romantic to the core, were among the top 10 box-office draws. Since then, however, not one romantic drama has cracked that list. The only love story this century to be among the five highest-grossing movies of its year was My Big Fat Greek Wedding. So the Kidman-Jackman epic, known by the least lovey-dovey name anyone could come up with, Australia, is, if not swimming against the tide, at least staring into a gritty desert wind...