Word: fatter
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...frequently cited in the media: America is a fatter country than ever. Levels of diabetes and other weight-related conditions are on the rise across all groups, and a larger percentage of Americans are classified as obese. Diet and exercise would seem to be obvious solutions, yet the national weight problem isn't getting any better. How can the country slim down on a nationwide level? What is the best way for society to alleviate one of its leading health problems...
...when his team deactivated the remaining 112 genes, the worms grew fatter...
...mesh. Some of the songs have a direct message; some have emotional meaning; and some, in gimlet-eyed retrospect, make you wonder why you ever picked them in the first place (this means you, Anna Nicole). But then you play that CD back on the stereo, a few older, fatter years later. Your toe taps. A memory comes back. And you realize that in that nonsensical mess of cotton-candy lyrics and throwaway choruses, you somehow managed to write down your life...
About one thing, however, there is no dispute. As a society we are clearly in a state of nutritional crisis and in need of radical remedies. The statistics are sobering. After 30 years of seemingly solid advice aimed at lowering dietary fat, Americans have grown collectively fatter than ever. Today more than 60% of adults in the U.S. are classified as overweight or obese. So many children have become so heavy that pediatricians are now facing an epidemic of Type 2 diabetes and hypertension--diseases that are closely associated with overweight and that were unheard of among youngsters just...
...balance. For as we layer on fat, we pump out more leptin, which signals the hypothalamus that it's time to accelerate energy output and brake caloric intake. The problem is, people who gain weight have now been shown to develop a remarkable resistance to leptin's power. The fatter they get, and the more leptin they make, the more impervious the hypothalamus becomes. Eventually the hypothalamus interprets the elevated level of leptin as normal--and forever after misreads the drops in leptin caused by weight loss as a starvation signal. This phenomenon provides a biochemical explanation...