Word: fda
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Dates: during 1950-1959
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After a quick and thorough check by topnotch authorities, the Food & Drug Administration gave its verdict last week. Chloromycetin was connected with the deaths of at least 72 aplastic anemia victims. However, there are "serious and sometimes fatal diseases in which its use is necessary," the FDA decided; therefore, doctors may still use it. But the manufacturers, Parke, Davis & Co., must warn doctors on the leaflet packed with every bottle that studies of the patient's blood are essential if Chloromycetin is given for a long time. Further. "Chloromycetin should not be used indiscriminately or for minor infections...
Lesson of History. Before the FDA acts, it will want to know whether the new drugs, given over long periods, will prove too poisonous for the patient to tolerate. Doctors want to know much more. Will the germs learn to resist the new drugs and live with them, as they often do with streptomycin? If a patient's sputum is free of germs a month after treatment is started, will it still be clear a year later, or will he suffer a shattering relapse...
Last week, with the FDA's blessing, Antabuse went on sale for general use on a doctor's prescription. It is no sure cure for alcoholism, but it is a useful crutch for the alcoholic cripple. Antabuse experts such as Manhattan Psychiatrist Ruth Fox argue that the alcoholic's other crutch should be psychiatric treatment. Dr. Fox has used both crutches with 149 patients, and got half of them to quit drinking entirely and another quarter of them well on the way. But Antabuse must be used under a doctor's supervision, warned Dr. Fox: "This...
Testosterone, a male sex hormone, is a fine thing when properly used. But the Food & Drug Administration warned this week that testosterone, ignorantly used, can stimulate the growth of cancers. The FDA was delighted that federal courts have barred two Los Angeles firms from peddling hormones without prescription...
Also under the court ban: sale of unprescribed female sex hormones (estrogens). Improperly used, said FDA, these may cause serious injury to women's reproductive organs...