Word: fda
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Dates: during 1950-1959
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...took until 1957 for the FDA to figure out by increasingly sensitive tests, that there is a minute residue of stilbestrol in other parts of caponettes than the head -20 to 30 parts per billion in the liver and 35 to 100 in the skin...
...average caponette weighs 2,500 gm. (about 5½ Ibs.). So, by the FDA's top-hazard figures, a roast-caponette fancier would get only a minute fraction of a milligram of stilbestrol if he ate all the skin fat and liver. Medical doses of stilbestrol for human patients cover a wide range beginning at .1 mg. daily, but often run to 15 mg. daily, and may go as high...
...strength of this tenuous evidence. Secretary Flemming decided to ban the use of stilbestrol in fattening fowl. (It will still be permitted in fattening cattle and sheep, because even FDA supersleuths have not been able to find any residue in these meats, provided that growers stop feeding the substance to the animals at least 48 hours before slaughtering.) Manufacturers agreed to stop selling stilbestrol to caponette raisers, and the farmers agreed to stop using stuff they will no ' longer be able to get. The Department of Agriculture was stuck with the job of buying up $10 million worth...
...Secretary Flemming's Food and Drug Administration was getting ready for another fight of the same sort last week-this time with the $80 million-a-year lipstick industry. FDA chemists charge that 17 different coal-tar dyes used in lipsticks caused either death or illness when fed to rats. The lipstick makers insist nonetheless that women never digest more than an infinitesimal speck of lipstick, and that the FDA's attack is grossly unfair. Probable next step: a public hearing to discuss FDA's ban on the dyes, now scheduled to go into effect...
Biggest complicating factor is a basic fact of pharmacology: there is no sharp line between poisonous and nonpoisonous substances-common salt can be a poison in excess, and arsenic can be a lifesaver. Dr. Arnold J. Lehman, the FDA's pharmacology director, quotes the Swiss Alchemist-Physician Paracelsus (1493-1541): "Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy." Some chemicals are poisonous over the years even in minute doses, and these the FDA will ban outright. But in the main, under its new legislative charter to protect...