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Word: fda (lookup in dictionary) (lookup stats)
Dates: during 1990-1999
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DCRI has been designed to find vital but frequently obscure medical information. Califf's favorite illustration involves an antiarrhythmia drug that had passed clinical trials, was approved by the FDA and was being given to thousands of patients before it was discovered that the drug was killing some patients. "You'd think that doctors would notice people falling over dead," says Califf. "But these things happen over years." These problems not only happen over time; they also often happen in patients who had other medical conditions that might have killed them. And they happen amid a large pool of people...

Author: /time Magazine | Title: More Science...And Much More Money | 10/12/1998 | See Source »

...that two experimental drugs decrease the duration and severity of influenza. Both--a pill called GS4104 and an inhaler named Relenza--also cut down on complications like bronchitis. And used daily for a month during flu season, Relenza can help keep you from getting sick in the first place. FDA approval may come...

Author: /time Magazine | Title: Your Health: Oct. 5, 1998 | 10/5/1998 | See Source »

Last week, for example, an FDA advisory panel recommended that the agency approve a new drug called Enbrel. The week before, the full FDA had given the nod to another anti-rheumatoid arthritis drug called Arava. Next month the agency will assess a promising blood-filtration device that clears the body of arthritis-promoting substances the same way kidney dialysis cleans the blood of toxins. Within a few months the FDA will also consider a new class of anti-inflammatories called COX-2 inhibitors (a.k.a. "super aspirin") that will attack arthritis pain. Says Steven Abramson, an FDA adviser and chief...

Author: /time Magazine | Title: Arthritis Under Arrest | 9/28/1998 | See Source »

...call for reinforcements. The COX-2 inhibitors target prostaglandin production, limiting pain and inflammation. And the blood-filtration device, invented at Cypress Bioscience of San Diego, strips the blood of proteins that tell white cells (erroneously) what tissues to attack--a treatment so effective in clinical trials that the FDA review-and-approval process has been put on a faster track...

Author: /time Magazine | Title: Arthritis Under Arrest | 9/28/1998 | See Source »

...herceptin, anything that can help women in the advanced stages of breast cancer is good news. It's not a cure and does nothing for the 70% of cases that don't involve the so-called HER-2 gene. But the drug has been in desperately short supply, and FDA approval should improve that situation...

Author: /time Magazine | Title: Breast Cancer | 9/14/1998 | See Source »

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