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Consider what happened with Rezulin, the diabetes drug that was taken off the market last week. The FDA approved the medication in 1997 after tests on 3,000 people showed that it could help control Type 2 (formerly adult-onset) diabetes, which affects 15 million Americans. Although some test subjects developed abnormal liver reactions, no one suffered permanent damage, and no one died. Now that millions have taken Rezulin, however, it has been linked to at least 90 cases of liver failure, 63 of which resulted in death...

Author: /time Magazine | Title: Diabetes Recall | 4/3/2000 | See Source »

When serious complications first started showing up, the FDA strengthened the warning labels on Rezulin and recommended regular liver tests for all patients using it. But not everyone got tested, and it was impossible to predict who would suffer a bad reaction. Then last year the FDA approved two new drugs (Actos and Avandia) that are chemically related to Rezulin but appear to be safer. Rezulin began looking like more trouble than it was worth...

Author: /time Magazine | Title: Diabetes Recall | 4/3/2000 | See Source »

Some critics have argued that the FDA waited too long to ask Warner-Lambert, Rezulin's manufacturer, to issue a recall. The pharmaceutical company still believes Rezulin is a good drug and blames the media for sensationalizing its risks. But if you're one of the 500,000 Americans currently taking Rezulin, what you need to know right now is how to get off the drug without jeopardizing your health...

Author: /time Magazine | Title: Diabetes Recall | 4/3/2000 | See Source »

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Author: /time Magazine | Title: News Quiz Crossword Mar. 27, 2000 | 3/27/2000 | See Source »

VIAGRA, UP OR DOWN? A confusing week for Viagra users. Preliminary analysis of cases reported to the FDA has found 1,500 heart attacks, arrhythmias and strokes--some fatal--in men who popped the impotence pill. Particularly troubling, most of the guys probably weren't on nitrates for angina or hypertension. (Nitrates are a no-no when taking Viagra.) Scary? Another study--financed by Pfizer, Viagra's maker--concludes that heart problems from the drug are rare, at least among low-risk men. If you're at all worried, check with your doc before checking out Viagra...

Author: /time Magazine | Title: More Heart News | 3/27/2000 | See Source »

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