Word: fibroblasts
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...claim was a bit grandiose. In fact, the scientists had mapped only a certain portion of the epigenomes of two cell types (an embryonic stem cell and another basic cell called a fibroblast). There are at least 210 cell types in the human body - and possibly far more, according to Ecker, the Salk biologist, who worked on the epigenome maps. Each of the 210 cell types is likely to have a different epigenome. That's why Ecker calls the $190 million grant from NIH "peanuts" compared with the probable end cost of figuring out what all the epigenetic marks...
That's what Dr. Weiss is after. The idea is to heat up the underlying dermis, stimulating fibroblast cells to produce collagen, which pushes out fine wrinkles and scars. "This temperature sensor is monitoring things," says Weiss, 49, as he points to a fail-safe device on the laser. "If the temperature rises too high in the skin, it won't let you do another pulse...
...when work about the firsttumor-derived angiogenesis factor--lateridentified as fibroblast growth factor--waspublished, researchers swarmed into the field.Biotechnology companies and researchers alikebegan researching angiogenesis with a frenzy...
...been removed. In mysterious ways scientists still do not understand, something in the cytoplasm of the egg appears to reset the donor cell's DNA. That resetting, it has been clear from the beginning, works much less reliably when adult cells are used, even when they are relatively immature fibroblast cells...
...Judah Folkman, Andrus professor of pediatric surgery and a professor of anatomy and cellular biology at the Medical School, a team of doctors discovered that basic fibroblast growth factor (bFGF) is present in the normal lining of the intestines and in ulcerated tissue. The team also found evidence that the growth factor may be critical in duodenal ulcer repair...