Word: fisherisms
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...reassemble an old musical needs a mix of showmanship and scholarship--a paleontologist's digging and Poirot's powers of inference. "Did they use this harmony, or did they mean it to be that harmony?" says Rob Fisher, 45, the series' musical director and local hero. "I agonize over this, because I want the score to sound exactly as it did originally." No reclamation project has been as daunting as that of St. Louis Woman. "There was no score," Fisher says, "just scraps of material." Ace orchestrators Ralph Burns and Luther Henderson re-created--and, for the overture and dance...
When Chase stumbles upon the body of Ella Fisher, a black dean, dead from an apparent fall, she's sure that the wrong kind of invisible hand is at work. She investigates the victim's death with two weapons: an analytical mind and an unabashed use of her feminine wiles. Flattering and flirting, she makes her way through the suspects: the playboy university president who promoted Fisher from the secretarial ranks, allegedly thanks to her talents between the sheets; a slimy comptroller with a repertoire of bilingual--but still awful--come-ons (as in, "You're looking recherche this evening...
...those demands in the late 1980s that made University of Pittsburgh surgeon Dr. Bernard Fisher and others take a second look at tamoxifen, which had been in use for a decade as a milder alternative to chemotherapy for treating breast cancer. They noticed that it not only helped keep cancer from returning in the affected breast but also cut in half the number of new cancers in the other breast. Animal studies suggested that tamoxifen latches on to receptors in breast-cancer cells that would ordinarily take up the hormone estrogen--a substance known to fuel the growth of cancer...
That being the case, Fisher and other researchers wondered whether this cell-starvation process could prevent breast cancer from taking hold in the first place. Thus in 1992 they began the federally funded, 13,388-participant, $50 million study of women at especially high risk; being over 60 was a qualification by itself. Participants could also be included if they had a combination of two or more close relatives who had had the disease, a first child late in life, and several previous biopsies of suspicious lumps...
These questions will be answered by future research. But what's more important, Fisher believes, is that science has finally demonstrated that breast cancer can be prevented. Most women, especially those at low risk, probably won't go on tamoxifen. But they may well end up taking the next generation of safer, tamoxifen-based drugs, which are already under development, or the generation after that. Until those drugs come along, Visco of the National Breast Cancer Coalition urges women to go slowly. "Wait," she says. "The best thing to do is wait...