Word: fk506
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...five years, he took a drug called cyclosporin that prevented his body from rejecting the alien organ. When that medicine no longer worked, his doctors at Children's Hospital in Pittsburgh performed a second transplant in 1992 and started him on what was then an experimental treatment called FK506. Given his long experience, he was probably better prepared than most people for the pain and discomfort antirejection drugs can sometimes cause. He had already outlived most of the children he had met in the hospital while awaiting the initial transplant...
Schreiber says of this work, FK506 taught us a lot about signal transduction--the way in which cells received signals and translate them into action...
...most important clinical applications of FK506 lies in organ transplants...
When a patient undergoes a transplant, there is a risk of the body rejection the new organ. Drugs like FK506 suppress the immune system's inclination to act against, and possibly reject, the new organ...
...says that the potential clinical applications of FK506 could be very important because it has fewer side effects and can be administered in much smaller concentrations than the immunosuppressants currently...