Word: flaw
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...Once thought rare, a mutation in a BREAST CANCER gene turns out to occur in 1% of Ashkenazi Jewish women. These findings, combined with data showing that 1% of that population carry a flaw in a different breast cancer gene, means that 1 in 50 Ashkenazi Jewish women may have inherited a risk for the disease...
...film is an elaborately plotted escapade featuring a pair of glamorous Hong Kong-based criminals, Li Ann and Mac (Sandrine Holt and Ivan Sergei). They are lovers whose most troublesome character flaw seems to be an addiction to hair gel. Li Ann also demonstrates an ability to probably run faster in a snug mini-skirt and high-heeled boots than even Dennis Rodman...
...Arrogant. It helps if this person is good-looking, too. No insecurity pierces this person's armor, not even when he or she knows that every other person in the house is trying to find every flaw. Until that one night, when he or she faces the camera, alone, in the dank basement, and confesses on national television that it has all been a masquerade, and "The Real World" has changed his or her life. This one is a real keeper...
...artsy. The nerd. The extracurricular king or queen. Come to think of it, the most interesting project of all might be to put seven Harvard people together in a house to find out what happens when they stop being polite and start being real. But there's one major flaw: Harvard people aren't polite to begin with. Let the auditions begin...
...measure of a happy few, generally students who had to be in the Twin Cities, who could not afford top schools or who found teachers and peers--as in the flagship units of the Liberal Arts, Political Science, Psychology and Economics Departments--who could mentor their work without flaw...