Word: flibanserin
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
...Flibanserin, however, does not act on hormones, and the new data suggest that it works in premenopausal women. "We don't yet understand the pathways. What we think is that in women with HSDD, there is likely an imbalance of serotonin, and that flibanserin is balancing the imbalance in these neurotransmitters," Sand says...
...flibanserin findings are based on the study of 1,378 premenopausal women who had been in a monogamous relationship for 10 years on average. The women were randomly assigned to take 100 mg of flibanserin or a placebo daily and to record daily whether they had sex and whether it was satisfying. The women were screened for depression and other medical conditions, and all had a diagnosis of HSDD...
Women in the flibanserin group self-reported 2.8 sexually satisfying events in the four-week baseline period; in the final four weeks of the 24-week study period, those women reported 4.5 sexually satisfying events, a more than 50% increase. Women in the placebo group reported an increase from 2.7 events to 3.7. The difference in effect between flibanserin and the placebo - about 0.8 sexually satisfying events - was statistically significant, the drug company said, and the side effects from the drug, which included dizziness and fatigue, among others, were mild to moderate and transient...
...could potentially improve sex for some women, others may be more harmed than helped. Debby Herbenick, a sex educator and researcher at Indiana University's Kinsey Institute, does not deny that there is a biological cause of low libido. But she raises another kind of concern about drugs like flibanserin: What if they work? "[The problem] is far more complex than not desiring sex. What we really have is a group of women who wonder why they don't desire their long-term partner the way they used to," Herbenick points out. "What happens if you suddenly do have desire...
That, of course, is not a side effect that was measured in any of the drug trials involving female sexual dysfunction - including those on flibanserin - and not one that will be weighed...