Word: florey
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...wonder drug penicillin (TIME, Feb. 8) is doing even better than expected. In the Lancet, Britain's H. W. Florey, who first sponsored the drug, recently described the largest series to date of penicillin-treated (and usually cured) cases. The patients had osteomyelitis, septicemia, eye infections, meningitis, chronic infected wounds. Findings...
...Florey believes some surgical operations might be revised to take advantage of penicillin, tried it in 22 cases of mastoid. Immediately after operation, the incision was stitched up with a small rubber tube running to the bottom of the wound and closed by a spigot. Every six hours the tube was drained and filled with a penicillin solution. After a week the tube was removed. Nineteen of the cases were healed and only three needed any further treatment...
...Florey reported the treatment of old wounds with draining sinuses. They were filled with penicillin solution and stoppered with a rubber bung. The solution was changed twice a day. Of eleven wounds which had persisted for three months to twelve years, seven healed in four weeks...
...Florey ended on the discouraging, realistic note that "penicillin is as yet available in only the smallest quantities." The A.M.A. gave a similar warning last week to U.S. doctors: though Merck & Co., E. R. Squibb & Sons, Charles Pfizer & Co and the Lederle Laboratories are all making penicillin, "in no instance has production advanced beyond the pilot-plant stage," and supplies for civilian use will be "exceedingly limited." The Army recently tried penicillin on a few veterans from the Pacific suffering from compound fractures, osteomyelitis and wound infections. First results were so good that the Medical Corps will soon extend trials...
...marvelous mold that saves lives when sulfa drugs fail was described in the British Lancet last month by Professor Howard Walter Florey and colleagues of Oxford.+ The healing principle, called penicillin, is extracted from the velvety-green Penicillium notatum, a relative of the cheese mold. Although it does not kill germs, the mold stops the growth of streptococci and staphylococci with a power "as great or greater than that of the most powerful antiseptics known." Once the germs are checked, the body's white blood cells finish them...