Word: folics
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Dates: during 1940-1949
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...Indian-born physiologist and biochemist, director of research for the Lederle Laboratories (American Cyanamid Co.); in Pearl River, N.Y. As a Harvard graduate student, he pioneered in studies on muscular contraction, after going to Lederle concentrated on folic acid (part of the vitamin-B complex), helped develop its derivatives, teropterin and aminopterin (now being used to fight cancer), directed research that produced the new antibiotic, aureomycin (a cure for serious infections untouched by penicillin or streptomycin...
...drug, called Teropterin, was developed by the Lederle Laboratories, and was first tried on animals and one patient at Mt. Sinai Hospital (TIME, Sept. 15). It is a vitaminlike chemical derived from folic acid...
Singleminded research has taken Dr. Tom D. Spies (rhymes with fees) deeper and deeper into the dim regions of deficiency diseases. It has also led him to major medical discoveries. Last week in Science he announced a new one with a report that folic acid, part of the vitamin B complex, was a remedy for tropical sprue, a widespread disease in such teeming, undernourished lands as Puerto Rico...
Spies, with associates at San Juan's School of Tropical Medicine, thinks that the efficacy of folic acid also proves decisively that sprue (symptoms: diarrhea, mouth sores, lassitude) is a result of poor diet rather than a contagious disease, as some doctors have insisted. Folic acid, Spies announced earlier this year in the A.M.A. Journal, is also a remedy for all but a few rare kinds of anemia, causing red blood cells to pour into the blood in striking numbers...
...uncertain: whether folic acid also halts the nerve degeneration common in anemia...