Word: folkman
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Because the tumors in question had been unresponsive to the traditional chemotherapy treatment, Folkman said, the study lends support to the theory that it is possible to halt and reverse cancer growth in mice with a "flanking maneuver"--targeting blood cells surrounding the tumor but not the tumor itself...
...provides additional evidence that tumors are angiogenesis-dependent, evidence for which has been piling up for 30 years now," Folkman said...
...Folkman said the findings suggest a new way to treat tumors that were thought to be untreatable because they were resistant to traditional chemotherapy drug treatments...
...results of the study are particularly important to Folkman and members of his laboratory team, who have been studying angiogenesis for about 30 years...
...Browder, who was working full-time in Folkman's laboratory, began experimenting with non-standard treatment regimens that utilized a standard chemotherapy drug, Cytoxan. He eventually developed a treatment schedule that appeared to inhibit the regeneration of endothelial cells--the cells that line blood vessels--in test mice...