Word: folkman
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...Medical School's Andrus Professor of Pediatric Surgery M. Judah Folkman announced last Friday that tests at his lab at the Children's Hospital had confirmed the effectiveness in mice of the protein fragment, called antiangiogenic antithrombin (aaAT), in suppressing the formation of blood vessels that feed tumor growth...
This discovery comes less than two years after Folkman published his lab's detection of the second of two protein fragments thought to suppress tumor growth. The three fragments have only been tested in animals, and it will be impossible to judge the potential of these substances in fighting human cancers until extensive clinical trials are held, at least...
...article in the journal Cell, researchers in Folkman's lab, including Folkman and angiostatin discoverer Michael S. O'Reilly, wrote that their findings and experimental data "suggest a theme of fragments of proteins as angiogenesis [blood vessel growth] inhibitors...
...protein's sequence was first analyzed at the Harvard Microchemistry Facility. William S. Lane, director of the facility, said that although his lab's high-tech equipment aided the discovery, it is the Folkman lab that should be congratulated...
...determined the peptide sequence," Lane said. "But kudos to Folkman and O'Reilly for isolating the protein," he stressed...