Word: folkman
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...result, Folkman stepped down assurgeon-in-chief at Children's Hospital, a post hehad held for fourteen years, to pursue researchfull-time...
Recently, the research Folkman began in 1961has led to some of the most promising discoveriesin cancer treatment. The isolation of angiogenesisinhibitors, endostatin and angiostatin, by Dr.Michael O'Reilly, a member of Folkman's researchgroup, has been a major breakthrough...
Using a combination of the two inhibitors,Folkman and his colleagues have eradicated largetumors in mice without causing side effects orsigns of drug resistance...
...development of drug resistance in cancerpatients to their chemotherapy can often be thefinal stage of their condition, but endostatin andangiostatin do not induce such reactions. Evenwith such exciting results, Folkman acknowledgesthat the ultimate step in his research is to beable to provide clinical treatment for humans...
...Folkman's office is inundated with hundreds ofphone calls from hopeful cancer patients and theirfamily members each day. Some have read in thenewspaper that one of the inhibitors has beenshown to regress leukemia. Others call to seekmedical guidance for cancer...