Word: folkman
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...When we put tumors in, they all stoppedgrowing at a millimeter or less," Folkman says."You could see it. The difference was in thethyroid gland with hemoglobin solutions, theendothelial cells along the blood vessels swelledup and prevented blood vessels from reaching thetumor. But when we moved the tumor to the animal,it grew and killed the animal. In 1961, we saw forthe first time that when you have no bloodvessels, tumors stopped growing...
...Folkman's observation became his lifelongpursuit, but the scientific community scoffed athis endeavor. Folkman says this was a blessing indisguise because it enabled him to conductresearch without the competition of his peers.Dividing his time between the operating room andthe research laboratory, Folkman dashed from thehospital to the lab and back each...
...Folkman and his research teampublished a paper that outlined the possibility ofangiogenesis factors and inhibitors...
...that time, we had only one post-doctoralfellow and two technicians," Folkman says. "Wecould work leisurely. No one believed anythinganyway...
...Folkman and his colleagues continued topublish more research results showing the link ofangiogenesis to cancer, other scientists began topay attention...