Word: folkman
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...seen a mouse tumor that we cannotregress," Folkman said in a speech before theNational Institutes of Health last year...
...nearly thirty years, Folkman and his laboratory partners have been working on a process called anti-angiogenesis, which has proven effective against all types of cancer and successfully eradicated tumors in small animals...
...Folkman and his colleagues at HMS have isolatedangiogenesis inhibitors, also known asanti-angiogenesis factors, which have been testedupon animals. TNP470 was the first inhibitorisolated from a fungus. Four more inhibitors havebeen subsequently discovered in the human body...
...Folkman garnered widespread skepticism from the scientific community when he became the first person to suggest that cancer growth is regulated by a switch that is turned on or off by the balance of angiogenesis factors and inhibitors...
...report published in the November 1997issue of Nature, Folkman and his researchteam demonstrated that one of the most powerfulinhibitors they had isolated, endostatin, couldsignificantly shrink tumors in mice...