Word: folkman
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...search for the drug began in the 1970s, when Dr. Judah Folkman, now Andrus professor of pediatric surgery at the Medical School, postulated that tumors, like other body tissue, were dependent upon blood supply to grow...
...Reilly discovered two proteins--endostatin and a similar, previously identified protein called angiostatin--in his efforts to test Folkman's hypothesis...
...significance of Folkman's finding lies in the protein's ability to inhibit angiogenesis (blood vessel growth), said Noel Bouck, a professor of microbiology and immunology at Northwestern University Medical School. "In order to grow, tumors must produce new blood vessels," she said...
...Folkman] realized if one cancer cell produced a little inhibitor, a large tumor produces many," Bouck said...
Colleagues praise Folkman's ground-breaking research...