Word: formalin
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Early this year Dr. Brodie, who works on Dr. Park's staff, discovered that, if he mashed the spinal cords of infected monkeys with formalin, the resultant mixture would immunize other monkeys against live virus...
...children under 15. Although all kinds of monkeys may serve for the manufacture of the vaccine, the best kind is Macacus rhesus from India. To import one rhesus monkey to the U.S. costs $9. After it is infected, killed, and its spinal cord ground up with formalin, at a processing cost of $3 more, the finished vaccine is only enough to inoculate twelve children. But even if $37,000,000 were available for nation-wide immunization, the supply of rhesus monkeys in India is by no means unlimited...
Infected Rhesus monkeys supplied the material for the vaccine. Just as the monkeys were dying of infantile paralysis, Dr. Brodie killed them, snatched out their spinal cords which contained the virus of the disease, macerated the cords in a solution of formalin to kill the virus. This virtually is what other investigators of the infantile paralysis problem are trying. Dr. Brodie seems to be the first to apply the vaccine to humans...
...National Institute of Health makes its toxoid by treating live scarlet fever bacilli with formalin and heat. After standing two months the germs lose their virulence, form with the antitoxin a bland but adequate protection against scarlet fever...
...dead bacteria of the same disease. But the acid-fast germs are encased in or contain fatty cells called " lipoids," which resist digestion when injected into the body and thus generate no antibodies. Dreyer's idea is to pickle the serum consisting of dead tubercle bacilli in formalin, a solution of formaldehyde. This eats away the fatty cells of the tubercle bacillus, which can then be digested by the body juices, and calls forth a plentiful supply of the antibodies when injected. They in turn attack and destroy the living germs of the disease. Dreyer inoculated three tuberculous guinea...