Word: formely
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...three new genes, known as clusterin, complement receptor 1 (CR1) and PICALM, were uncovered by two separate research groups, one in Wales and one in France, who linked the genes to the most common form of the memory disorder, late-onset Alzheimer's - the type that affects patients in their 60s or later and accounts for about 90% of all Alzheimer's cases. The only other gene connected with the condition, apolipoprotein E (ApoE), was identified in 1993; since, researchers have tirelessly hunted for other key genes, knowing that 60% to 80% of the progressive, incurable disease is genetically based...
...discoveries mark a significant step forward in Alzheimer's research - until now, three of the four known genes associated with the disease were connected to the rarer, inherited form, which appears in adults as young as 40 or 50. The three additional genes, identified in the new papers, now tip the balance of genetic understanding in favor of the late onset condition that affects a majority of the 5.3 million patients living with the disease in the U.S. (See how to prevent illness...
...these genes, two - clusterin and CR1 - are known to interact with the amyloid protein that builds up in the brain of Alzheimer's patients and eventually causes nerve cell death and cognitive problems. Clusterin may be involved in helping to clear away the amyloid that forms in the brain; but another variant of the gene may also allow amyloid to form fibrils, the sticky protein arms that further anchor amyloid plaques to nerve cells, much like a spider web ensnares prey. In late-onset Alzheimer's, it's possible that the body cannot balance these two functions of clusterin...
...spent four years as a propaganda artist, portraying North Korean leader Kim Jong Il in unvaryingly heroic poses, but now the painter Sunmu is having fun with the form. Since arriving in the South in 2001, 38-year-old Sunmu - it's an assumed name - has been lampooning his old master from a musty studio in a run-down suburb of western Seoul. In the eponymous work Kim Jong Il, the North Korean supremo is shown in a pink tracksuit, grinning and fat. In Please Have Some Medicine (pictured), he is a dying hospital patient being offered Coca-Cola...
About a week after their initial placement in the yard, we wondered, how are the colored chairs doing? We know they are meant to serve as a "new form of gathering space," so are they performing...