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...turns to this line of work when Lila (Misty Upham), an outcast from the Indian reservation, steals her car, which is ideal for smuggling - capacious trunk and a dashboard release button, handy for quickly off-loading human cargo should trouble arise. The two women form an uneasy partnership and, of course, bad things do start to haunt them. There are the cops and the border patrol to worry about. Also the dangerous scumbags who run the smuggling ring. And the possibility that the ice on the river might crack under the car's weight...
...Kevin Eggan at the Harvard Stem Cell Institute and Christopher Henderson at Columbia University, the 13-person team reported online today in Science Express that they had generated motor neurons from the skin cells of two elderly patients with a rare form of ALS, or Lou Gehrig's disease, a progressive neurodegenerative condition. The new study marks an important first step on the road toward real stem-cell-based therapies, and also answers several plaguing questions about the pioneering stem-cell technique known as induced pluripotent stem cell, or iPS, generation...
...rapid growth has also placed unprecedented strains on Macau's society, in the form of soaring property prices, labor unrest, overburdened infrastructure and discontent among residents like Ng who feel their lives have been made worse, not better, by Macau's renaissance. Foreigners have flooded in with the boom and are competing with natives for plum jobs. Transportation systems have been taxed to breaking point by the 27 million tourists who visited last year. Calls for change have forced the government to scramble to appease a disgruntled public. "The gaming industry has been infiltrating into the community and creating...
...City's subway averages 26 suicides a year. In Paris, 24 died on the tracks of the Métro last year. While it is a fallacy to imagine any suicide as a solitary act - even the tidiest affair leaves survivors stricken - death by train is a particularly declaratory form of killing oneself. It makes the act a form of theater - for the driver, watching it all from behind his windshield, and for the rest...
...therapies might curb plaque formation but leave the tangles alone. One theory is that the drugs normalize the communication network of insulin receptors, which go awry in the Alzheimer's brain, somehow restoring those pathways to as close to normal as possible, while clearing out the damaging plaques that form when the network malfunctions. "Our hypothesis is that with the combination therapy, the gene and protein expression of these Alzheimer's patients might be close to that of normal people who don't have Alzheimer's at all," she says. Beeri stresses that it's far too early to recommend...