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...review published in the Jan. 20 issue of the Cochrane Database of Systematic Reviews, a leading evidence-based-medicine journal, researchers found that only one-third of 1% of chronic-pain patients without a history of substance problems became addicted to opioids during treatment. The review included 4,893 mostly middle-aged chronic-pain patients, who were treated with opioids for between six months and four years. "This suggests that people who do not have a history of drug abuse or addiction are not highly like to develop [addiction] under physician care," says Meredith Noble, lead author of the review...

Author: /time Magazine | Title: Are Doctors Too Reluctant to Prescribe Opioids? | 2/24/2010 | See Source »

...Overdose Problem For the most recent study of overdose risk, researchers examined the medical records of nearly 10,000 chronic-pain patients being treated within a Washington State health plan between 1997 and 2005. Published in the Annals of Internal Medicine in January, the study found that 51 patients had experienced overdose - six of them fatal. The overall risk of overdose was small, but it was clearly associated with the dose of the medication originally prescribed: patients receiving the highest doses were nearly nine times more likely to overdose than patients on the lowest doses. "The overall risk among people...

Author: /time Magazine | Title: Are Doctors Too Reluctant to Prescribe Opioids? | 2/24/2010 | See Source »

...condition. From “Raging Bull,” the sports movie that focused on the violent imperfections of human nature, to “The Departed,” a police procedural/gangland thriller that studied loyalty, betrayal, and identity in a disconcertingly harsh light, he has always found a way to push past the cliché, the obvious, and the mundane. With “Shutter Island,” Scorsese turns his attention to a new genre: the psychological thriller. A mind-bending, atmospheric film with a couple of vertigo-inducing twists and turns...

Author: By Daniel K. Lakhdhir, CRIMSON STAFF WRITER | Title: Shutter Island | 2/23/2010 | See Source »

...thought-provoking message. We expect great ideas, new innovations, broken boundaries. We expect, in short, a film that is different, one that will stay with us well past the final fade-to-black. And it is this essential point where “Shutter Island” is found lacking. It is competent, but also vaguely utilitarian—fun while it lasts, but slight in lasting impact. And that, from Scorsese, is simply inadequate...

Author: By Daniel K. Lakhdhir, CRIMSON STAFF WRITER | Title: Shutter Island | 2/23/2010 | See Source »

...film student Alexandra E. Zimbler ’10 visited her grandmother in Saint-Malo, Brittany, to interview her for her documentary thesis film in Visual and Environmental Studies (VES). She had planned to make a film about her grandmother’s life in a nursing home, but found her main character in the early stages of Alzheimer’s disease. “She didn’t have her memory any more,” Zimbler said. “I went to her old apartment, looking for photographs, anything that would give me clues about...

Author: By Abigail B. Lind and Rebecca A. Schuetz, CRIMSON STAFF WRITERS | Title: The Scenic Route | 2/23/2010 | See Source »

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