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Researchers discovered the first antidepressants purely by chance in the 1950s. Seeking a treatment for schizophrenia, scientists at the Munsterlingen asylum in Switzerland found that a drug that tweaked the balance of the brain's neurotransmitters - the chemicals that control mood, pain and other sensations - sent patients into bouts of euphoria. For schizophrenics, of course, that only made their condition worse. But researchers soon realized it made their pill perfect for patients with depression. On first trying it in 1955, some patients found themselves newly sociable and energetic and called the drug a "miracle cure." The drug, called imipramine...
More worrying than concerns about overprescription, however, are the implications of a study in the January issue of the Archives of General Psychiatry that found that half of depressed Americans don't get the treatment they need. On that score, experts say, prospective patients ought not to be scared off by the skepticism over antidepressants and should consult their doctors to find a course of treatment. In the nearly two decades since he published Listening to Prozac, Kramer notes, the standards of care have risen and the options have increased. "If people are doing badly," he tells TIME, "there...
...whenever Massachusetts wasn’t converting lay-ups, it seemed, it was converting foul shots. All four Crimson post players—juniors Emma Markley and Claire Wheeler and freshmen Victoria Lippert and Miriam Rutzen—found themselves in foul trouble...
...more than three decades, the Sea Shepherd Conservation Society has rammed, sabotaged and shot stink bombs at whalers and commercial fishermen. Watson founded Sea Shepherd's forerunner Earth Force Society in 1977, and since then, he and his organization have not shied away from controversy. He has attacked Greenpeace, an organization he also helped found, calling the group "the Avon Ladies of the environmental movement" because of their allegedly wimpy tactics. Over the years, Watson has come under firearms attack four times, according to his website. In a 2008 Whale Wars episode that some critics have said was faked, Watson...
...intelligence sharing to fight terrorism have never been better. Both officials downplayed the tit for tat between London and Washington earlier this week over comments from British authorities that the domestic spy agency MI5 had given U.S. authorities early intelligence on Abdulmutallab. (It hadn't, because British authorities found no evidence that the Nigerian had been radicalized while studying in London from 2005 to 2008 and thus had no reason to sound alarm bells...