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...matter what its configuration, angiostatin could not make a mouse tumor disappear. Not, that is, until Folkman and O'Reilly added to the mix a second molecular fragment, which they called endostatin, from yet another naturally occurring protein. Together, the two compounds destroyed a range of tumors in mice. The results were startling enough that they merited testing in people--which is exactly what Pluda, at the National Cancer Institute, intends to do. How fast those studies can begin depends on how much angiostatin and endostatin EntreMed and its business partner, Bristol-Myers Squibb, can produce and whether they...

Author: /time Magazine | Title: The Hope & The Hype | 5/18/1998 | See Source »

...collection begins with a fragment from 1923 that is among the earliest known surviving symphony-broadcast recordings. At first its sound seems irritatingly thin and scratchy, but as the listener's ears adapt, the focus turns to Willem van Hoogstraten's white-hot, meticulously sculpted rendering of most of Beethoven's Coriolanus overture; the level of orchestral precision is breathtaking. Even more remarkable is Willem Mengelberg's spellbinding presentation in 1924 of two fragments from Richard Strauss's Death and Transfiguration. Mengelberg achieves an almost spiritual intimacy in the work's tender, meditative broodings and a radiant beauty...

Author: /time Magazine | Title: Music: Glory from a Golden Past | 1/26/1998 | See Source »

...President's formidable mind, he pulls out his scissors and begins snipping. He whittles a page down to a paragraph, the paragraph down to a sentence and that sentence down to the one key phrase that contains, for Gore, the essence of the whole idea. Then he arranges the fragment on his desk among the other scraps of paper--seeds of thought, if you will--already lying there. "You just pray nobody sneezes," says Carol Browner, who rose from Gore's staff to become head of the Environmental Protection Agency. After the idea has ripened on his desk, he will...

Author: /time Magazine | Title: CAN AL GORE BARE HIS SOUL? | 12/15/1997 | See Source »

...home. I may have learned to suppress the observation and block it out. And who could blame me? When done right, the bagel can serve as the focal point for an entire diet. But in the hands of lesser baker...it's nothing more than a carbohydrate-rich sandwich fragment...

Author: By Dan S. Abel, | Title: A Crisis of Bagels | 12/3/1997 | See Source »

...unique and priceless source of data," are only now beginning to gain public attention because they remained classified for several years. About 20 or 30 minutes had been declassified in 1983, but the major portion of the recordings weren't declassified until fall of 1996. The last fragment was released early this year...

Author: By Erwin R. Rosinberg, CRIMSON STAFF WRITER | Title: Cold War Warrior Listens To Kennedy | 9/18/1997 | See Source »

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