Word: frayed
(lookup in dictionary)
(lookup stats)
Dates: during 1990-1999
Sort By: most recent first
(reverse)
...Silvermine Consulting Group, in Westport, Connecticut. "It's the most dramatic medical launch since Advil." Two acid blockers, Tagamet HB and Pepcid AC, have begun battling it out for market share, and two more--including the British colossus Zantac in over-the-counter form--will be joining the fray by next year...
...Pepcid's quick strike, Tagamet's ambitious counterattack and the row over advertising may look like mere skirmishes when Zantac 75 enters the fray. This acid blocker is the over-the-counter version of Zantac, the top-selling prescription drug in the world and the pride of Britain's Glaxo-Wellcome pharmaceutical stable. Prescribed for 240 million patients around the globe, Zantac last year generated $3.6 billion in sales, $2.1 billion in the U.S. And last month the over-the-counter Zantac 75 received a recommendation from an FDA advisory committee, virtually assuring its imminent approval for sale...
...firms in the fray or about to enter it are only too aware that their new heartburn drugs are bound to cannibalize their traditional antacid products. In touting Tagamet HB, for example, SmithKline has to avoid invidious comparisons with Tums, its antacid moneymaker, while J&J/Merck must tiptoe around any comparisons between Pepcid AC and its antacid, the much advertised Mylanta. Meanwhile, Switzerland's Ciba-Geigy has other worries. Though it has no acid blocker available that could bite into sales of Maalox, its bread-and-butter antacid, its competitors' new drugs almost certainly will...
Such brinkmanship is anathema to Dole, who stayed above the fray, struggling to maintain his balance between running for President for the third time and running the Senate. As Dole shuttles--sometimes daily--between Washington and New Hampshire, the juggling act has begun to take a noticeable toll. In the Senate, Dole has made several unforced errors lately, puzzling lawmakers who have long relied on his dealmaking acumen and keen sense of timing...
Leaping into the fray last week, President Clinton told a thousand cheering supporters at a Congressional Hispanic Caucus dinner, "The issue is whether or not we're going to value the culture, the traditions of everybody and also recognize that we have a solemn obligation to let these children live up to the fullest of their God-given capabilities." But the issue does not divide purely along partisan lines. Although House Speaker Newt Gingrich and G.O.P. presidential hopefuls Richard Lugar and Patrick Buchanan back the English-only movement, G.O.P. Governor George Bush of Texas left popular bilingual programs untouched...