Word: fridovich
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Dates: during 1990-1999
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...phone interview yesterday, Irwin Fridovich, a professor of bio chemistry at Duke University Medical Center, proposed several possible explanations for the increased susceptibility of neurons to decreased SOD levels in ALS patients...
...Fridovich said neurons may produce more free radicals than other cells, or may have less ability to repair damage, or may simply be more sensitive to superoxide levels...
...Fridovich said he anticipates that further experiments with the altered SOD will find the protein less active, and that accumulation of damage to cells caused by superoxides not eliminated by SOD could eventually cause the death of many cells...