Word: fruitlessness
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...activity in the caudate nucleus, but it's specifically in a part that's adjacent to a brain region associated with addiction. If the two areas indeed overlap, as Fisher suspects, that helps explain why telling a jilted lover that it's time to move on can be fruitless-as fruitless as admonishing a drunk to put a cork in the bottle...
...unusually elusive. Since the establishment of Israel in 1948, the region has been devastated by three major wars and numerous insurgencies on what are today Palestinian territories known as the West Bank and the Gaza Strip. The efforts of many U.S. presidents and several supposed breakthroughs have proved fruitless. This millennium, the prospects for peace have seemed unusually bleak: More than a thousand Israelis have been killed as a direct result of the terrorist tactics employed by Fatah, Hamas and other Palestinian groups since 2000, while Israeli counterattacks and military operations have killed more than 4,000 Palestinians...
...while it looks as if his tenure as Treasury Secretary would be remembered chiefly for his repeated and apparently fruitless trips to China to persuade authorities there to do something about their huge trade surpluses with the U.S. Now it's becoming clear that Henry Paulson's legacy will be determined instead by his success or failure in navigating the financial crisis that began earlier this year in the U.S. subprime-mortgage market and has since spread around the globe...
...lurid tale began on March 21, 2002, when Darwin paddled his red kayak into the North Sea in front of his seafront home in Seaton Carew, near Hartlepool. He never returned. An oar drifted ashore the next day, and after a fruitless search, the shattered remains of his vessel were found on a local beach six weeks later. Despite this evidence, suspicion lingered that there was something incongruous about an experienced kayaker drowning on a day when the sea was, in the words of one member of the rescue effort, "smooth as a millpond." Even before it emerged that...
...hawks are warning that diplomacy is fruitless, and that the President will be forced before the end of his term to choose between military action and accepting a nuclear-armed Iran. The President's former U.N. ambassador John Bolton is openly complaining that Bush is betraying his own best instincts under the malign influence of "pragmatists" such as Secretary of State Condoleezza Rice...