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Manufactured by Fujisawa Pharmaceutical of Osaka, FK-506 is derived from a soil fungus found in Japan. Starzl first learned of the drug in 1986 at a meeting in Helsinki. Other researchers had dismissed it because in studies using dogs it caused severe bleeding and other problems. But Starzl believed the reaction occurred in dogs alone and undertook a graduated series of experiments on several other animals, from rats to baboons. These tests were encouraging, and in February 1989 Starzl tried the drug on Robin Ford, a 26- year-old secretary who was in danger of rejecting her third liver...

Author: /time Magazine | Title: Medicine: Lifesaver Drug | 10/30/1989 | See Source »

...moated Imperial Palace to watch and pray. Tens of thousands lined up to sign visitors' books at the main palace gate and elsewhere throughout the country. Autumn festivals, including Tokyo's Grand Ginza extravaganza, were canceled, as was the 100th-anniversary celebration of the daily Asahi Shimbun. Said Mitsu Fujisawa, 112, believed to be the oldest person in Japan: "I have worshiped His Majesty for a long time. I hope he will recover and live longer than I have...

Author: /time Magazine | Title: Japan Vigil for a Failing Emperor | 10/3/1988 | See Source »

...Fujisawa Municipal Gymnasium (1982) exemplifies the impeccable craft of his best work since then. Like much Japanese architecture of the past 25 years, it has a sci-fi quality: one section of the building resembles some enormous otherworldly blimp, the other calls to mind a high-tech samurai helmet. But unlike the slicker gimmicky UFO architecture (Kurokawa's earlier work, for instance), Maki's gym is restrained and sober, a mature fantasy. The flawless, parabolic stainless-steel skin is 1.6 acres in size but just about one-sixtieth of an inch thick...

Author: /time Magazine | Title: Design: Japan Is On The Go | 9/21/1987 | See Source »

Michio Arai Fujisawa, Japan...

Author: /time Magazine | Title: Letters: Dec. 27, 1982 | 12/27/1982 | See Source »

DIED. Tetsu Katayama, 90, the only Japanese Socialist leader ever to become Prime Minister; in Fujisawa City, Japan. Katayama helped form Japan's Socialist Party in 1945, and was voted into office as Prime Minister two years later in the country's first postwar elections. A fair-minded idealist who championed laborers and tenant farmers, he proved an ineffectual leader when his campaign compromises with political factions of the coalition government sapped his authority. Nine months into his term, with his economic policies failing badly, he resigned, crying, "All I want is sleep, sleep!" and retired...

Author: /time Magazine | Title: Milestones, Jun. 12, 1978 | 6/12/1978 | See Source »

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