Word: functionally
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Dates: during 2000-2009
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...these malignant cells. Current drug-based treatment works by blocking ERs, thus slowing or stopping tumor growth. The study identified sections of DNA known as control regions, portions of genes pertaining to cell growth and division that bind to the ER. These control regions remotely activate or inhibit the function of the gene. The researchers created a map of all of these regions—several thousand in total. Since genes have multiple control regions, the map indicates that approximately one thousand genes are influenced by the binding of estrogen to the ER, according to a statement released by Dana...
...midst of redesigning 13.5 acres of the Wellesley campus. According to the society’s website, the plan involves the restoration of the campus’s Alumnae Valley—for the last several years a parking lot—to its former natural landscape and function as part of a natural hydrological system. The firm removed tons of toxic soil and raised the entire level of the valley six feet. Van Valkenburgh Associates has completed four projects at Wellesley to date, and six projects are currently underway. The award judges, comprised of the society?...
...plans. Though this process may be error-laden and oftentimes without a clear marketable value at its endpoint, it is a process which is crucial to personal development. The responsibility for ensuring that colleges perform as they should lies on the individual student. No administration from above can function well as a surrogate for this...
...last month. A research team led by James Sikela of the University of Colorado at Denver and Health Sciences Center, in Aurora, Colo., looked at a gene that is believed to code for a piece of protein, called DUF1220, found in areas of the brain associated with higher cognitive function. The gene comes in multiple copies in a wide range of primates--but, the scientists found, humans carry the most copies. African great apes have substantially fewer copies, and the number found in more distant kin--orangutans and Old World monkeys--drops off even more...
...region that changed most dramatically from chimps to humans, known as HAR1, turns out to be part of a gene that is active in fetal brain tissue only between the seventh and 19th weeks of gestation. Although the gene's precise function is unknown, that happens to be the period when a protein called reelin helps the human cerebral cortex develop its characteristic six-layer structure. What makes the team's research especially intriguing is that all but two of the HARs lie in those enigmatic functional noncoding regions of the genome, supporting the idea that much of the difference...