Word: functionally
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Dates: during 2000-2009
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...year, 94% of the kidneys that were perfused had survived once transplanted, compared with 90% of the cold-stored kidneys. More significantly, 26% of the cold-stored organs failed to function in the first weeks after transplant, compared with only 21% of the kidneys that were perfused. While the differences were small, say experts, they can be significant when you consider the costs of dialysis and follow-up care for failed transplants. "Four percent may not appear to be a lot, but if this difference persisted across the country, that would be a significant cost benefit on behalf...
Cohen suggests that a better understanding of novelty-seeking behavior may even help researchers find more effective treatments for addiction. If future studies validate Zald's findings and show that addicts also have fewer dopamine-inhibiting receptors than average, then medicines designed to replace the function of those receptors may help bring their dopamine levels down to normal and weaken their addiction...
...first sign of Parkinson's. The latest thinking on the disease holds that the uncontrolled movements that are the hallmark of Parkinson's are only the latest and most advanced sign of the disease, the final stage of a 10- or 20-year gradual decline in nerve function. In fact, experts believe that the condition actually begins with a loss of smell and a degeneration of nerves in the olfactory tract, then proceeds to the gut and brain stem. At some point along this march, the nerve damage hits the pons, a region in the brain that regulates sleep...
...sleep disorder itself can be treated with medications, but those drugs won't slow the decline in nerve function that's responsible for Parkinson's. But identifying the disease at this earlier stage may help scientists come up with newer ways of protecting the motor neurons from further damage. "We don't have agents now to stop the degeneration of Parkinson's," says Postuma. "But once we have those agents, as far as I'm concerned, every patient with REM sleep disorder should be taking...
...that the projects that he and his colleagues from other institutions embarked on were “more scientifically adventurous than is typical” of work funded with money from federal agencies like the National Institutes of Health. Kahn, for instance, received Picower grants to investigate a potential function of fat cells that she said was too preliminary to gain federal support at the time. With the funding stream from Picower unexpectedly shut off, it is unclear whether the researchers will be able to continue the innovative work...