Word: gabuzda
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
Unlike in the body, where HIV only destroys immune cells, Gabuzda says that the infection of microglia--the brain's counterpart to white blood cells--is responsible for the release of neurotoxins, which damage neurons...
...Gabuzda used this discovery to try to find out if any of these proteins allowed HIV into microglia. She found that CCR5, and another protein--CCR3--are part of the complex that is the brain's gate...
These molecules had been suspected of being able to channel HIV "but this had only been suggested in recombinant DNA experiments," says Gabuzda. "This is the first time CCR3 has been shown to be the doorway...
...known that people who are deficient in the CCR3 receptor show no known abnormality, and further that they are highly resistant to HIV infection," says Gabuzda...
...Theoritically even if HIV were eliminated totally by other drugs from the body, it could resurface from hiding in the brain.' --Dan H. Gabuzda, Associate Professor of Neurology, Dana-Farber Cancer Insititute