Word: gallos
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Last year, after months of feuding, the Pasteur team, headed by Dr. Luc Montagnier, filed two legal actions in the U.S. The first challenged a patent on the blood test awarded to Dr. Robert Gallo and his colleagues. The second charged Gallo with breach of contract for allegedly using for commercial purposes samples of virus sent to him by the French. Gallo had agreed to use the samples for research purposes only...
...Moreover, the Patent Office recognized the French as the "senior party," since their patent application was filed seven months earlier than the NIH application. Now, says Charles Lipsey, a patent attorney for Pasteur, "the burden of proving that they invented the test first is going to rest on Dr. Gallo...
...Gallo has long maintained that no matter who actually discovered the virus, his lab was first to grow large quantities of it; this tricky step, he insists, was crucial to developing a workable blood test. "We had the science first," says Acting Assistant Secretary of Health Donald Macdonald. "We feel strong in our position." But mass-producing the virus "doesn't matter," counters Lipsey. "What matters is who made the invention first...
...news of an apparently harmless relative of the AIDS virus was greeted with enthusiasm by other scientists. "The best thing about Max's virus," says Gallo, "is that we can learn why one is pathogenic and the other isn't." By identifying which component of the AIDS virus is responsible for its deadly effects, researchers may be able to develop new drugs that specifically inhibit it. They may also be able to alter the virus genetically to remove its harmful traits, leaving a benign version that could serve as a vaccine...
Late last week research teams in both Gallo's and Haseltine's laboratories revealed that they had already succeeded in tinkering with the AIDS virus and rendering it inactive. They did so by snipping out a gene that enables the virus to replicate with remarkable speed. Without the gene, the viruses "don't kill T cells and don't reproduce anymore," says Haseltine. The "dead-ended" virus, he notes, could serve as a prototype for a vaccine...