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...alcoholics have about half as much alcohol dehydrogenase as their healthy counterparts, but alcoholic women show almost no enzyme activity at all. The falloff may result from alcohol's injuring the stomach wall, where the enzyme is manufactured. Whatever the cause, "alcoholic women appear to lose all gastric protection," says Dr. Charles Lieber of Mount Sinai School of Medicine in New York City, who collaborated on the study with Dr. Mario Frezza of the University School of Medicine in Trieste, Italy. "For them to drink alcohol is the same as shooting it up directly into their veins...

Author: /time Magazine | Title: Health: Why Men Can Outdrink Women | 1/22/1990 | See Source »

...Fred may be able to counter the effects of his gastric binges if he has enough of the HDL vigilantes in his blood. Largely produced in the liver and the intestines, these flat, disklike particles resemble "empty envelopes waiting to be filled," says Dr. Norman Miller, head of endocrinology at North Carolina's Bowman-Gray School of Medicine. As the VLDL and chylomicron particles unload their triglyceride cargoes into the body's cells, the particles become wrinkled like prunes. In the process, fragments containing proteins, fats and cholesterol break away. It is at this point that the unfilled HDL particles...

Author: /time Magazine | Title: Medicine: Searching for Life's Elixir: HDL, the good cholesterol | 12/12/1988 | See Source »

Garn will serve mainly as the shuttle's human guinea pig. He will be subjected to tests designed to increase understanding of space motion sickness, an affliction suffered by about half the people who go into orbit. In one of the "gastric motility" experiments, stethoscopic microphones were strapped to the Senator's midsection to record his stomach noises at takeoff (NASA has yet to release a tape of the senatorial rumblings). Said Garn: "I am hopeful that I can fill in a few of the pieces of the puzzle in the medical department...

Author: /time Magazine | Title: Jake Skywalker: A Senator boards the shuttle | 4/22/1985 | See Source »

...circulatory disorder that causes painfully cold hands and feet), gastric ulcers and colitis. "Ten or 15 years ago, we thought there was no therapy for stress," says Stanford Psychiatrist Stewart Agras. "Now we know that relaxation is not a gimmick; it works...

Author: /time Magazine | Title: Stress: Can We Cope? | 6/6/1983 | See Source »

Some physical disorders appear to be linked to an imbalance of prostaglandins. Too little of a type that regulates gastric acid and protects the stomach lining has a role in the development of ulcers. Too much of a PG that causes uterine contraction may provoke menstrual cramps. Other PGs play a part in arthritis, while leukotrienes, PG-related compounds identified by Samuelsson, are implicated in asthma...

Author: /time Magazine | Title: Medicine: Sharing the Nobel Prize | 10/25/1982 | See Source »

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