Word: gaziano
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...Neither doctors nor patients may want to drop cholesterol testing altogether - more information is better, especially when the consequence of missing a diagnosis is heart attack - but there is still a practical lesson to be learned. "I think in the U.S. we might use this as an initial test," Gaziano says. "We can at least narrow the group of people for whom we need to screen cholesterol." Those with very few other heart-disease risk factors, for example, probably don't need the extra blood work, since their cholesterol profile wouldn't make a big difference to overall risk anyway...
...researchers, led by Thomas Gaziano at Harvard Medical School and Brigham & Women's Hospital in Boston, trawled through data on 6,186 American adults participating in the U.S. National Health and Nutrition Examination Survey. Participants were initially examined in the early 1970s and had no prior history of cardiovascular disease; they were tracked for 21 years, during which time 1,529 of the participants suffered cardiovascular events (such as heart attacks, stroke, angina or heart failure), including 578 deaths due to heart disease...
...Gaziano and his colleagues show that if simple measurements, like BMI, are thoughtfully considered, doctors with fewer resources in the developing world can screen for heart-disease risk just as effectively as their counterparts in high-income countries. There is some question about whether results from the U.S. can be applied accurately to other populations - for a given BMI, for example, Asians tend to have a higher body-fat ratio than Caucasians - but, in many ways, Americans of the 1970s may be more similar than not to populations elsewhere today. In the '70s, Americans smoked a lot more tobacco than...
...study, published in the Oct. 22 issue of the Archives of Internal Medicine, Associate Professor of Medicine J. Michael Gaziano and Assistant Professor of Medicine Luc Djousse, researchers at the Harvard-affiliated Brigham and Women’s Hospital, analyzed data from a 1981 study of physicians’ health...
...evidence is incontrovertible. Merck [the company that manufactures Vioxx] itself admitted that it found a doubling of heart attack and stroke in Vioxx users in a randomized trial it conducted. That’s why it took the drug off the market.”Gaziano, a cardiologist who has never done Vioxx research, said he feels the evidence is insufficient and that more research is needed.“I don’t believe there is a link for short-term use,” he said in an interview. “Questions have been raised about...