Word: gene
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Dates: during 1970-1979
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...five man Crimson contingent--coach Dave Zewinski '76, seniors George Hughes, Gene Purdy and Jon Stein and sophomore Tommy Murray--had entered the International University Sports Fishing Seminar and Competition which has been sponsored by the town of Yarmouth, Nova Scotia since...
...Gene Williams '81 characterized the new owners as "ridiculously polite...
...many public alarms have been sounded lately about the possible perils of genetic engineering that its vast potential for good has often been overlooked. Now that imbalance should be somewhat corrected. Last week, after months of careful, skillful and imaginative use of the new gene-splicing techniques, California scientists announced that they had achieved a long sought goal: the creation in the lab of a microbe that can manufacture human-type insulin...
...insulin with bacteria, making the finished human variety posed greater difficulties. For it consists of two distinct molecular chains, a so-called A strand and a B strand, each of which is produced separately inside the cells of the pancreas under the direction of its own characteristic gene...
Synthesizing copies of these genes, or segments of DNA (deoxyribonucleic acid), was difficult enough. But much harder was the job of getting the genetic instructions inside the potential bacterial factory, a weakened lab strain of the intestinal microbe Escherichia coli. The scientists resorted to a little molecular chicanery. Using their new gene-splicing or recombinant DNA techniques, they hitched their two synthetic insulin genes individually to one of the bacterium's own genes. Then they inserted both the synthetic and the natural material into fresh E. coli. As a result, E. coli's DNA-reading machinery was unable...