Word: gened
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...team of researchers at Harvard-affiliated Mass. General Hospital recently developed a therapy to suppress brain tumor growth by using a cancer-killing gene delivered via a virus vector to cells surrounding the tumor. Testing their treatment on mice, they said, yielded “spectacular” results...
...that, Casey A. Maguire, the lead author of the study, used “adeno-associated virus vectors”—the best vectors for global delivery—to introduce a gene that, when expressed, causes production of the protein interferon-beta...
After four days, the size of the tumor in mice with the beta-interferon gene had been substantially reduced compared to the mice that had not received the gene...
Within two weeks, the tumors had been completely eliminated in mice with the interferon-beta gene...
Another benefit of creating a “zone of resistance” is that when the gene is injected in one side of the brain, it can eliminate a tumor on the other, or contralateral, side, according to Anat O. Stemmer-Rachamimov, a pathologist at MGH and another of the study’s authors...