Word: gened
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...also a tutor for over two years with the Refugee Youth Enrichment’s term-time program, said Gene A. Corbin, the executive director of PBHA. Corbin described Fienning as “very passionate about serving others,” noting that he was “sure service would have continued to be a big part of his life...
...find out whether Hwang's stem cells came from a single egg, Daley's team, which included leading researchers from England, Japan and Canada, conducted a whole-genome analysis of the DNA from Hwang's stem cell line. By analyzing tens of thousands of gene snippets on the cells' genomes, and comparing these signatures to those of the egg donor and of the skin cell donor, they were able to determine that the DNA fingerprint of the stem cells was consistent with that of the egg. "The genetic signature of a parthenote is very very obvious," says Daley. Because...
...disorder comes to you through the genes, the next job is to determine which ones. A team of investigators at Johns Hopkins University last summer discovered half a dozen areas in the human genome that appear to be linked to the development of OCD. Analyzing 1,008 blood samples from 219 families in which at least two siblings had the disorder, they discovered gene markers at six sites on five chromosomes that appear more frequently in those kids than in family members and other people without OCD. That study did not tease out how those genes do their damage...
Located on the ninth chromosome, that gene--discovered in two studies by researchers at several universities including the University of Michigan and the University of Toronto--appears to regulate a brain chemical known as glutamate. One of a number of substances that stimulate signaling among neurons, glutamate works fine unless you've got too much on hand. Then the signals just keep coming. In the case of the alarm centers in the brain, that means the warning bell just keeps on ringing. "Glutamate has to be taken up quickly because otherwise it becomes toxic to the brain cells," says Vladimir...
What makes the glutamate-related gene especially suspect is the particular people it affects the most. OCD strikes males and females about evenly, but early-onset forms tend to target boys more than girls. This is particularly true in cases in which the boys also exhibit the involuntary tics or vocalizations often associated with Tourette's syndrome. Interacting with the glutamate gene are three genes related to androgens, or masculinizing hormones. Interacting with those is another gene that has been implicated in Tourette's. Gather all these together in the same chromosomal neighborhood, and they can make trouble. "Kids...