Word: genee
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...study published on June 16 in the Journal of the American Medical Association (JAMA) now threatens to send researchers back to the drawing board. The meta-analysis of 14 prior studies concludes that the so-called depression gene - a variant of a serotonin-transporter gene called 5-HTTLPR - may not be associated with an elevated risk for depression, as many researchers had believed. "Knowing whether or not you have this gene is irrelevant," says the study's co-author Kathleen Merikangas, a genetic epidemiologist at the National Institute of Mental Health, who adds that future studies of genetic risk factors...
...discovery by Duke psychologist Avshalom Caspi of a "depression gene," which was among the first to be associated with mental illness - a notably difficult class of diseases to pin down, genetically speaking - inspired dozens of similar studies. While many researchers had suspected that 5-HTTLPR played a significant role in depression risk, Caspi was the first to establish an association by studying depressed people who had also experienced a stressful life event, such as the death of a child or sudden unemployment. What Caspi's 2003 epidemiological study, published in Science, found was that people with one or two copies...
...will surpass that caught in the wild for the first time, according to the United Nations Food and Agriculture Organization. But most fish farms - even ones heralded as "sustainable" - create as many problems as they solve, from fecal contamination to the threat that escaped cultivated fish pose to the gene pool of their wild cousins. (See pictures of tuna fishing...
Beaver cites last month's prevention study as key to understanding how to best make use of his latest findings on MAO-A and gang membership. If policymakers wish to prevent violence, he says, money would be better spent not hunting for gene-based drugs, say, but expanding and improving neighborhood-based intervention programs, such as early childhood education and after-school activities...
...much easier and cost-effective to modulate an individual's environment than it is to alter their genetic code," says Buckholtz. And until the gene is better understood, that investment will pay off for those with the MAO-A defect and those without...