Word: genentech
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...NASCAR racers of entrepreneurship, injecting fuel--private investment dollars--into new companies that are exciting but may come apart at high speeds. It's a high-risk profession. They have driven important new technologies to market, creating new jobs and new industries. Apple Computer, eBay, biotechnology pioneer Genentech, Federal Express and, most notable of late, Google, all grew out of daring private investments. In the 1990s "suddenly venture capitalists became rock stars," says Mark Heesen, president of the National Venture Capital Association. Since 1970 venture capitalists (VCs) have pumped $339 billion into start-ups; these companies have created 10.1 million...
When the FDA approved Genentech's colorectal cancer drug Avastin last week, it also validated a cancer-fighting strategy proposed more than 30 years ago. Avastin is the first in what researchers hope will be a whole new class of drugs called angiogenesis inhibitors, which attack tumors by thwarting their ability to create blood vessels--thus starving cancer cells of oxygen and nutrients. In trials, Avastin has been shown to give patients, on average, an additional five months of life. Cost of a 10month course of treatment: about...
...biotechnology research company Genentech, Inc. began testing Avastin in September 2003. Avastin is a genetically-engineered protein that binds to and neutralizes vascular endothelial growth factor, a protein that spurs the growth of blood vessels surrounding a cancerous tumor...
That may soon change. Researchers are looking beyond aspirin and other multipurpose medications to experimental drugs that block inflammation more precisely. Any day now, Genentech is expecting a decision from the FDA on its colon-cancer drug, Avastin, which targets one of the growth factors released by the body as inflammation gives way to healing. Millennium Pharmaceuticals is testing a different kind of drug, called Velcade, which has already been approved for treating multiple myeloma, against lung cancer and other malignancies. But there is a sense that much more basic research into the nature of inflammation needs to be done...
RAPTIVA For people who suffer from psoriasis, there may be relief--and convenience--in this new drug awaiting FDA approval. With a weekly injection, Genentech's Raptiva prevents certain immune cells from migrating to the skin's surface, where they trigger abnormal growth and create the disease's hallmark lesions...