Word: genes
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Dates: during 2000-2009
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...team of researchers at Harvard-affiliated Mass. General Hospital recently developed a therapy to suppress brain tumor growth by using a cancer-killing gene delivered via a virus vector to cells surrounding the tumor. Testing their treatment on mice, they said, yielded “spectacular” results...
...World Trade Center.) But the real fascination is how the show plays off the techno-expectations about police work that CSI has bred into us. With no computers or lab work, Sam has to chase his case '70s-style, with shoe leather and - as his new boss, Lieutenant Gene Hunt (Harvey Keitel), demonstrates - a healthy disregard for search warrants...
...being one of the largest investors in a red-hot area of drug research: ribonucleic-acid-mediated interference, or RNAi for short. First identified a decade ago, RNAi is a mechanism that exists naturally within all cells. Its discovery offered scientists one of the first clues into how genes can be turned on and off. And since many diseases are caused by a malfunction of specific genes, the ability to control their expression through RNAi has enormous therapeutic potential. "As soon as we identify what gene to target, our pipeline could be full of new medications for any number...
Roche, however, retains one key advantage: it has already seen its own line of attack succeed. The proof? Roche's first targeted breast-cancer drug, Herceptin. Developed by Genentech, Herceptin was marketed specifically to destroy cancers containing the her-2/neu protein, which doctors can detect using a 21-gene screen diagnostic. Herceptin has helped thousands of women combat breast cancer. But there's no doubt it has also helped Roche's bottom line: at $40,000 a year per patient, Herceptin grew globally in sales nearly 25%, to $4.1 billion, last year. "You need self-confidence to take risks...
...work on a gene and when you knock it out you lose the whole throat, but you get a little worm and it actually is born and crawls around on the plate” Mango said. “The first time I saw the mutant phenotype I was just completely smitten...