Word: genes
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Dates: during 2000-2009
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...Gene G. Ketelhohn, the Cabot House building manager who had been a spirited presence in House life for decades, died last Saturday night, May 26. He was 60. Ketelhohn suffered from inoperable liver cancer, according to Cabot Assistant to the Masters Susan Livingston. He had worked in the House for 23 years, so long that it was called South House when he first became superintendent. Livingston noted that despite Ketelhohn’s illness in the months before his death, he still enthusiastically participated in many of his favorite activities around Cabot. Livingston remembers Ketelhohn’s dedication...
...Every now and then nature throws up these sorts of things.' RUSSELL SNELL, New Zealand biotech researcher, whose company is breeding cows that give skimmed milk. The herd descends from a single Friesian cow named Marge, which scientists discovered had a rare gene mutation for low-fat, Omega 3-rich milk while testing New Zealand dairy cows...
...trial at Moorfields is not a conceptual breakthrough for the young science of gene therapy - there have been other trials on procedures in other organs - but, as a milestone, it's a good marker of where the field stands today. At its most basic, gene therapy is anything that introduces new genetic material to help fight or prevent a disorder. Treatment options are still in the experimental stages, and are not free of philosophical critics. But gene therapy has also been heralded as a potential cure for all kinds of genetic diseases (think cystic fibrosis or sickle-cell anemia...
...taken ingenuity. In patients like Robert Johnson, Ali delivers the functional gene using a virus that's been modified so it won't attack the eye or reproduce. The two trial subjects so far have not had severe immune responses to the new matter in their eyes - always a danger. Scientists are especially hopeful because the procedure worked so well in its animal trials. Scanning the eyes of dogs that underwent the procedure, researchers could see how the photoreceptor cells had changed. More important, the previously blind dogs could see well enough to navigate through a maze...
...says he expects it will be at least a year - and probably longer -before any results of his trial are published. It can take months for the new genes to take effect. He is, however, "optimistic." He's not alone. "I don't have any doubt this is going to be a real home run. The people in this trial, they're going to be out playing Frisbee, seeing their girlfriends' and boyfriends' faces for the first time," says Jeffrey Boatright, a self-described "second-generation" gene-therapy researcher at Emory University in Atlanta. The U.S. National Eye Institute issued...