Word: geneses
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Determining why the age-of-onset figures are in free fall is attracting a lot of research attention. Some experts believe that kids are being tipped into bipolar disorder by family and school stress, recreational-drug use and perhaps even a collection of genes that express themselves more aggressively in...
A decidedly more complicated explanation may be gene penetrance; not every generation of a family susceptible to an illness develops it in the same way. Often, later generations suffer worse than earlier ones because of a genetic mechanism known as trinucleotide repeat expansion. Defective sequences of genes may grow longer...
The first part of determining how those genes work is figuring out where they are hiding, and the National Institute of Mental Health is looking hard. Investigators at eight research centers around the country, working under an NIMH grant, are studying the genomes of 500 families with a bipolar history...
The last, perhaps hardest element of treatment is family therapy. Bipolar disorder, like schizophrenia, depression and certain anxiety conditions, is powerfully influenced by surroundings. When an identical twin suffers from bipolar, the other twin has only a 65% chance of developing it too. Conversely, adopted children with no genetic legacy...
Farther down the road, villages spring from the shrubbery, most of them decimated in the violence of 1999, but now alive with children seemingly in competition with the Thais for claim to the title "The Land of Smiles." Poor though they may be?indeed, East Timor is now officially the...