Word: geneses
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To find out whether Hwang's stem cells came from a single egg, Daley's team, which included leading researchers from England, Japan and Canada, conducted a whole-genome analysis of the DNA from Hwang's stem cell line. By analyzing tens of thousands of gene snippets on the cells...
What doctors didn't know was why these immune cells went into a hyperalert state to begin with. Was it caused by a virus? Was it nutritional, as suggested by a study last week in the journal Neurology, which found that having too little vitamin D, normally produced in the...
What they found were two new genes, IL2 and IL7, which code for receptors for interleukin - the proteins that regulate how T cells work in the body. People with certain forms of these genes have a 20% increased risk of developing MS. It is not, however, a defective or mutated...
As exciting as the discovery is, it's a small part of the story: the new genes account for less than 1% of the risk of developing MS. In addition, about 70% of the normal, non-MS affected population has the same variants. "Every single time we have looked for...
Hafler acknowledges that these findings are only the first step. Uncovering additional genes will require analyzing an even larger pool of MS patients and their families - Hafler is hoping to find at least 9,000 more patients. He calculates that with that much DNA, he'll be able to tease...